Cardiac Enzyme Studies

CK (Creatine Kinase), CPK (Creatine Phosphokinase), Creatine Kinase (CK), Creatine Phosphokinase (CPK), Creatine Phosphokinase-MB Isoenzyme (CPK-MB), Heart Attack Enzymes, Lactic Acid Dehydrogenase (LDH), LDH-1 (Lactate Dehydrogenase Isoenzymes)

Test Overview

Cardiac enzyme studies measure the levels of the enzyme creatine phosphokinase (CPK, CK) and the protein troponin (TnI, TnT) in the blood. Low levels of these enzymes and proteins are normally found in your blood, but if your heart muscle is injured, such as from a heart attack, the enzymes and proteins leak out of damaged heart muscle cells, and their levels in the bloodstream rise.

Because some of these enzymes and proteins are also found in other body tissues, their levels in the blood may rise when those other tissues are damaged. Cardiac enzyme studies must always be compared with your symptoms, your physical examination findings, and electrocardiogram (EKG, ECG) results.

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Author:	Douglas Dana Maria G. Essig, MS, ELS Robin Parks, MS	Last Updated: November 2, 2007
Medical Review:	Anne C. Poinier, MD - Internal Medicine E. Gregory Thompson, MD - Internal Medicine Stephen Fort, MD, MRCP, FRCPC - Interventional Cardiology
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